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Inflection Biosciences Ltd

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Inflection Biosciences is developing innovative therapeutics for the treatment of unmet needs in cancer. It has partnered AUM302 a first-in-class PIM/PI3K/mTOR inhibitor, while IBL-202, a first-in-class PIM/PI3K inhibitor is being progressed in CLL.

Dublin, Dublin, Ireland

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Inflection Biosciences Ltd

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Inflection Biosciences Ltd, based in Dublin, is developing small molecule therapeutics for the treatment of cancer. The company's pipeline of highly innovative cancer treatments was licensed from the Spanish National Cancer Research Centre (CNIO). AUM302 is a first-in-class, orally available PIM/PI3K/mTOR inhibitor, partnered with AUM Biosciences. Pre-clincal proof of conept in breast cancer, lung cancer, AML and neuroblastoma has been generated, with results published in peer...

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Inflection Biosciences Ltd, based in Dublin, is developing small molecule therapeutics for the treatment of cancer. The company's pipeline of highly innovative cancer treatments was licensed from the Spanish National Cancer Research Centre (CNIO). AUM302 is a first-in-class, orally available PIM/PI3K/mTOR inhibitor, partnered with AUM Biosciences. Pre-clincal proof of conept in breast cancer, lung cancer, AML and neuroblastoma has been generated, with results published in peer review EMBO Molecular Medicine in 2019. Data generated supports commencement of IND/CTA enabling studies. IBL-202 is a first-in-class PIM/PI3K inhibitor with pre-clincial data supporting its potential in chronic lymphocytic leukemia (CLL) (data published in peer review British Journal of Hematology in 2018) and related B-cell lymphomas including MCL and DLBCL. The IBL-100 series comprises selective pan-PIM kinase inhibitors with pre-clinical proof of concept in AML and lung cancer. The quality of company's research has been recognised in its receipt of funding from the European Union's Horizon 2020 in 2019. Inflection Biosciences was named ‘Start-up Company of the Year’ at the 2014 Irish Pharma Awards. For more information please visit www.inflectionbio.com

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Certifications

Seal of Excellence
The Seal of Excellence is a quality label awarded to project proposals submitted to Horizon 2020 which succeeded a highly competitive evaluation process by independent experts, but did not received funding due to budget limits. This quality label is a guarantee for investors to find high standard project proposals from European SMEs with growth potential.
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InvestHorizon
InvestHorizon is an accelerator programme designed to facilitate the access to Series A funding for selected DEEP TECH companies.
413 Members

Our history

Start in 31/12/2012

  • 31/12/2012

    Inflection Biosciences Ltd incorporated in Dublin, Ireland

  • 28/05/2013

    Cancer pipeline secure via licensing agreement with Spanish National Cancer Research Centre (CNIO)

  • 1/12/2012

    Initial seed round completed with private investor

  • 28/5/2013

    Investment secured from Irish Sovereign, Enterprise Ireland

  • 1/5/2017

    In vivo proof of concept with IBL-302 in breast, lung, AML, neuroblastoma

to be continued ...